Targeting of p21-Activated Kinase 4 Radiosensitizes Glioblastoma Cells via Impaired DNA Repair
Glioblastoma is a devastating malignant disease with poor patient overall survival.Strong invasiveness and resistance to radiochemotherapy have challenged the identification of molecular targets that can finally improve treatment outcomes.This study evaluates the influence of all six known p21-activated kinase (PAK) protein family members on the in